clomiphene for men

The maximum clomiphene for men concentration in the blood plasma of 109 ug / ml, time to maximum plasma concentration – 1.18 h, binding to blood proteins do not exceed 10%.

Injection: Maximum concentration  .. In plasma after intramuscular administration – 399 ug / ml, time to maximum concentration – 0, 84 hours after intramuscular and 0.1 h after intravenous injection, the volume of 318.0 ml, the absolute degree of biological 34.6% availability. At high concentrations steroids for sale uk
the drug accumulates in the tissues of the heart, liver, spleen, kidney and colon, in small amounts – in the small intestine and lung.

Indications
of liver toxicity, including alcoholic or viral origin and the drug (antibiotics, antineoplastic, antitubercular, antiviral drugs, tricyclic antidepressants, oral contraceptives, etc.). Chronic alcoholic hepatitis moderate minimal activity. Chronic viral hepatitis, fatty liver, cirrhosis of the liver.

Contraindications
: Hypersensitivity to the drug; renal failure; childhood; during pregnancy and lactation.

. Dosage and administration . Inside  appoint 1 – 2 tablets 3-4 times a day for 20 – 30 days. Duration of treatment is determined by the physician individually depending on the severity and characteristics of the disease.

Parenterally. In chronic hepatitis clomiphene for men in the first five days of illness injected intramuscularly with 2 ml of 2.5% solution 2-3 times a day (2-3 x 50 mg), or by slow intravenous injection at a rate of 2 ml / min 4 ml of a 2.5% solution (100 mg) or a drip at a rate of 20-30 drops per minute (2 ampoules of 2.5% solution dissolved in 150-250 ml of saline). From the fifth day to the twentieth  treatment prescribed tablets (100 mg three times a day). The course of treatment – 20-30 days.

. Side effects
Rarely:

  • from the gastrointestinal tract: nausea, dry mouth, flatulence;
  • from the central and peripheral nervous system: general weakness, dizziness, tinnitus;
  • on the part of the cardiovascular system: tachycardia, increased blood pressure, chest pain, arrhythmia;
  • on the part of the respiratory system: very rarely – shortness of breath, attacks of breathlessness.
  • allergic reactions: hypersensitivity reactions, fever, rarely – angioedema.
  • with the skin: itching, flushing of the skin, urticaria.

 

Overdose.
Cases of overdose are unknown clomiphene for men. If ingestion of a large amount of the drug – it is necessary to do a gastric lavage. Treatment is symptomatic.

. Cautions
The composition includes sucrose tablet – 2.8 mg per one tablet i.e. maximum daily dosage (8 tablets) contains 22.4 mg of sucrose, which should be considered in patients with diabetes mellitus.